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HDAC4 Mouse anti-Human, Clone: OTI4A4, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF805010

Encompass_Preferred

Catalog No. 50-166-7248


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Mutations to the HDAC4 gene have been found in Brachydactyly-mental retardation syndrome (BDMR).
Specifications

Specifications

HDAC4
Monoclonal
Unconjugated
HDAC4
AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA
Mouse
Affinity Chromatography
RUO
9759
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI4A4
PBS with 8% trehalose and no preservative; pH 7.3
P56524
HDAC4
Full length human recombit protein of human HDAC4 produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG1
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