HDAC6 (internal)Rabbit anti-Human, Polyclonal, Rockland™

Rabbit Polyclonal Antibody

Supplier:  Rockland Immunochemicals 600401J39

Catalog No. 50-199-2230

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. A BLAST analysis was used to suggest cross-reactivity with monkey and human based on 100% sequence homology. Cross-reactivity with HDAC6 from other sources has not been determined.

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

Specifications

• Antigen: HDAC6 (internal)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HDAC6
• Gene Alias: CPBHM; FLJ16239; HD6; HDA6; Hdac5; HDAC6; histone deacetylase 5; Histone deacetylase 6; Histone deacetylase mHDA2; JM21; KIAA0901; mHDA2; PPP1R90; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Sfc6
• Host Species: Rabbit
• Regulatory Status: RUO
• Gene ID (Entrez): 10013
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot
• Concentration: 1.09 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl, 30% glycerol and 0.05% sodium azide; pH 7.2
• Gene Accession No.: Q9UBN7
• Gene Symbols: HDAC6
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody