Invitrogen™ HDAC6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120113

Catalog No. PIPA5120113

Description

Positive test controls include: Rat liver. The target is usually found in the following locations: Cell projection, Cytoplasm, Nucleus, Perikaryon, axon, dendrite. Immunogen sequence: VMKVEDREGP SSSKLVTKKA PQPAKPRLAE RMTTREKKVL EAGMGKVTSA SFGEESTPGQ TNSETAVVAL TQDQPSEAAT GGATLAQTIS EAAIGGAMLG QTTSEEAVGG ATPDQTTSEE TVGGAILDQT TSEDAVGGAT LGQTTSEEAV GGATLAQTTS EAAMEGATLD QTTSEEAPGG TELIQTPLAS STDHQTPPTS PVQGTTPQIS PSTLIGSLRT LELGSESQGA SESQAPGEEN LLGEAAGGQD MADSMLMQGS RGLTDQAIF.

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

Specifications

• Antigen: HDAC6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HDAC6
• Gene Alias: CPBHM; FLJ16239; Hd6; HDA6; Hdac5; Hdac6; histone deacetylase 5; histone deacetylase 6; Histone deacetylase mHDA2; JM21; KIAA0901; mHDA2; PPP1R90; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Sfc6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10013, 84581
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.36 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UBN7
• Gene Symbols: HDAC6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 836-1104 of human HDAC6 (NP_006035.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov