Invitrogen™ HDAC7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596625

Catalog No. PIPA596625

Description

Positive Samples: NIH/3T3, A-549, MCF7, Jurkat, Mouse lung, Mouse heart, Mouse brain, Rat brain; Cellular Location: Cytoplasm, Nucleus Immunogen sequence: LRQIPSAEDL ETDGGGPGQV VDDGLEHREL GHGQPEARGP APLQQHPQVL LWEQQRLAGR LPRGSTGDTV LLPLAQGGHR PLSRAQSSPA APASLSAPEP A.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: HDAC7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HDAC7
• Gene Alias: 5830434K02Rik; HD7; HD7a; hdac4l; Hdac7; hdac-7; Hdac7a; histone deacetylase 7; Histone deacetylase 7A; mFLJ00062
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51564, 56233, 84582
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.12 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8C2B3, Q8WUI4, Q99P96
• Gene Symbols: HDAC7
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human HDAC7 (XP_0115367831).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG