Invitrogen™ HDC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529509

Catalog No. PIPA529509

Description

Recommended positive controls: Jurkat, Raji, K562, NCI-H929. Predicted reactivity: Mouse (92%), Rat (91%), Chicken (81%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The biogenic amine histamine is an important modulator of numerous physiologic processes, including neurotransmission, gastric acid secretion, and smooth muscle tone. The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase (HDC; EC 4.1.1.22). This homodimeric enzyme is a pyridoxal phosphate (PLP)-dependent decarboxylase and is highly specific for its histidine substrate.

Specifications

• Antigen: HDC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hdc
• Gene Alias: AW108189; HDC; Hdc-a; Hdc-c; Hdc-e; Hdc-s; histidine decarboxylase; L-histidine decarboxylase; MGC163399
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3067
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P19113
• Gene Symbols: Hdc
• Immunogen: Recombinant protein encompassing a sequence within the center region of human HDC. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG