Gibco™ Heat Stable FGF-10 Recombinant Protein

Description

Recombinant Protein

FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.

Specifications

• Accession Number: O15520
• For Use With (Application): Functional Assay
• Formulation: protein with 20 mM Na2PO4, 750 mM NaCl and no preservative; pH 7.5
• Gene ID (Entrez): 2255
• Name: Heat Stable FGF-10
• Purification Method: SDS-Page
• Quantity: 5 μg
• Endotoxin Concentration: 0.25 EU/μg
• Gene Alias: AEY17; BB213776; FGF; Fgf10; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10; Gsfaey17; Keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria
• Common Name: FGF10
• Biological Activity: ED50 = 1.0 ng/mL; measured in a cell proliferation assay using 4 MBr-5 cells
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Sequence: Thermostable variant of human FGF-10 (190 amino acids) with proprietary amino acid substitutions
• Buffer: 750 mM NaCl, 20 mM Na2PO4
• Content And Storage: -20°Cor to +80°C if preferred
• Classification: Recombinant
• Activity: ED50 ≤1.0 ng/mL; measured in a cell proliferation assay using 4 MBr-5 cells
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: >95% by SDS-PAGE

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov