Invitrogen™ Heavy chain of IgG4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115398

Catalog No. PIPA5115398

Description

Antibody detects endogenous levels of total IgG4.

The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.

Specifications

• Antigen: Heavy chain of IgG4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IGHG4
• Gene Alias: IGHG4; Immunoglobulin G; immunoglobulin heavy constant gamma 4 (G4m marker); ImmunoglobulinG; ImmunoglobulinG4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3503
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P01861
• Gene Symbols: IGHG4
• Immunogen: A synthesized peptide derived from human IGHG4(Accession P01861), corresponding to amino acid residues K88-E138.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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