Invitrogen™ Heavy chain of IgG4 Polyclonal Antibody

Catalog No.	Quantity
PIPA5115398	100 μL

Catalog No. PIPA5115398 Supplier Invitrogen™ Supplier No. PA5115398

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IgG4.

The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.

Specifications

• Antigen: Heavy chain of IgG4
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: IGHG4
• Gene Accession No.: P01861
• Gene Alias: IGHG4; Immunoglobulin G; immunoglobulin heavy constant gamma 4 (G4m marker); ImmunoglobulinG; ImmunoglobulinG4
• Gene Symbols: IGHG4
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human IGHG4(Accession P01861), corresponding to amino acid residues K88-E138.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3503
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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