Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA596314

Invitrogen™ HEC1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA596314
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA596314 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA596314 Supplier Invitrogen™ Supplier No. PA596314
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: ETIKQENTRL QNIIDNQKYS VADIERINHE RNELQQTINK LTKDLEAEQQ KLWNEELKYA RGKEAIETQL AEYHKLARKL KLIPKGAENS KGYDFEIKFN PEAGANCLVK YRAQVYVPLK ELLNETEEEI NKALNKKMGL EDTLEQLNAM ITESKRSVRT LKEEVQKLDD LYQQKIKEAE EEDEKCASEL ESLEKHKHLL ESTVNQGLSE AMNELDAVQR EYQLVVQTTT EERRKVGNNL QRLLEMVATH VGSVEKHLEE QIAKVDREYE ECMSEDLSEN IKEIRDKYEK KATLIKSSEE; Positive Samples: K-562, Lovo, MCF7, 22Rv1, THP-1, 293T, Mouse testis; Cellular Location: Chromosome, Nucleus, centromere, kinetochore.

Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HEC1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.49 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene NDC80
Gene Accession No. O14777, Q9D0F1
Gene Alias 2610020P18Rik; AV139730; HEC; HEC1; HEC-1; HEC2; HEC4; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; kinetochore protein Hec1; Kinetochore protein NDC80 homolog; kinetochore-associated protein 2; KNTC2; NDC80; NDC80 homolog, kinetochore complex component; NDC80 homolog, kinetochore complex component (S. cerevisiae); NDC80 kinetochore complex component; NDC80 kinetochore complex component homolog; NDC80, kinetochore complex component; putative kinetochore protein NDC80 like protein; retinoblastoma-associated protein HEC; TID3
Gene Symbols NDC80
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 343-642 of human HEC1/HEC1/NDC80 (NP_0060921).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10403, 67052
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.