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Invitrogen™ HEC1 Polyclonal Antibody
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Catalog No. PIPA5111613
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100 μL
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PIPA5111613 100 μL
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Catalog No. PIPA5111613 Supplier Invitrogen™ Supplier No. PA5111613
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CYESFMSGAD SFDEMNAELQ SKLKDLFNVD AFKLESLEAK NRALNEQIAR LEQEREKEPN RLESLRKLKA SLQGDVQKYQ Highest antigen sequence indentity to the following orthologs: Rat - 76%, Mouse - 78%.

Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HEC1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NDC80
Gene Accession No. O14777
Gene Alias 2610020P18Rik; AV139730; HEC; HEC1; HEC-1; HEC2; HEC4; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; kinetochore protein Hec1; Kinetochore protein NDC80 homolog; kinetochore-associated protein 2; KNTC2; NDC80; NDC80 homolog, kinetochore complex component; NDC80 homolog, kinetochore complex component (S. cerevisiae); NDC80 kinetochore complex component; NDC80 kinetochore complex component homolog; NDC80, kinetochore complex component; putative kinetochore protein NDC80 like protein; retinoblastoma-associated protein HEC; TID3
Gene Symbols NDC80
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human HEC1. Recombinant protein control fragment (Product #RP-105391).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10403
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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