Invitrogen™ HEC1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518089

Catalog No. PIPA518089

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.

Specifications

• Antigen: HEC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDC80
• Gene Alias: 2610020P18Rik; AV139730; HEC; HEC1; HEC-1; HEC2; HEC4; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; hsNDC80; kinetochore associated 2; kinetochore protein Hec1; Kinetochore protein NDC80 homolog; kinetochore-associated protein 2; KNTC2; NDC80; NDC80 homolog, kinetochore complex component; NDC80 homolog, kinetochore complex component (S. cerevisiae); NDC80 kinetochore complex component; NDC80 kinetochore complex component homolog; NDC80, kinetochore complex component; putative kinetochore protein NDC80 like protein; retinoblastoma-associated protein HEC; TID3
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10403
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O14777
• Gene Symbols: NDC80
• Immunogen: Synthetic peptide sequence (YEKKATLIKSSEE) corresponding to the C-terminus amino acids of NDC80 (aa 630-642).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG