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Invitrogen™ HECW1 Polyclonal Antibody
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Catalog No. PIPA564914
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100 μL
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Catalog No. Quantity
PIPA564914 100 μL
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Catalog No. PIPA564914 Supplier Invitrogen™ Supplier No. PA564914
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: STEPESAQIQD SPMNNLMESG SGEPRSEAPE SSESWKPEQL GEGSVPDGPG NQSIELSRPA EEAAVITEAG DQGMVSVGPE GAGELLAQVQ KDIQPAPSAE ELAEQLDLGE EASALLLEDG EAPAS Highest antigen sequence identity to the following orthologs - mouse 45%, rat 44%.

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HECW1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene HECW1
Gene Accession No. Q76N89
Gene Alias E3 ubiquitin-protein ligase HECW1; HECT type E3 ubiquitin ligase; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1; HECT, C2 and WW domain-containing protein 1; HECT-type E3 ubiquitin transferase HECW1; HECW1; hNEDL1; KIAA0322; NEDD4-like E3 ubiquitin-protein ligase 1; NEDD4-like ubiquitin-protein ligase 1; NEDL1; RGD1561038
Gene Symbols HECW1
Host Species Rabbit
Immunogen Recombinant Human HECW1. Recombinant protein control fragment (Product #RP-89679).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23072
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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