Hemagglutinin Rabbit anti-Virus, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0808	100 μL

Catalog No. 50-198-0808 Supplier Bioss Supplier No. BS10320R

Description

Rabbit Polyclonal Antibody

Hemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80% of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.

Specifications

• Antigen: Hemagglutinin
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from hemagglutinin [Influenza A virus A/environment/North Dakota/NWRC185233-06/2007 (H3N1)].
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG