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Precipio™ HemeScreen BCR/ABL1 Panel-20

The HemeScreen BCR/ABL1 Panel-20 is an RUO reagent set kit used to screen for 3 major BCR/ABL1 isoforms (p190, p210, and p230) and 1 minor isoform (p203) associated with BCR/ABL1-induced leukemogenesis, including CML and ALL using HRM methods.

Supplier:  Precipio™ HS20RBCR

Catalog No. 22-021-973


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Description

Description

HemeScreen is a proprietary set of RUO (Research Use Only) reagents used to screen the wild type (Negative) from Mutated (Positive) genes in a simplified workflow relative to alternative molecular testing technologies (RT-PCR or NGS).

  • Isoforms tested: p190, p203, p210, p230
  • Simplified workflow and reduced chance of error
  • Data capture during thermocycling
  • Fast turnaround time
  • Broad mutation detection (SNPs, Modifications, Indels)
  • Low limits of detection
  • Results are qualitative and DNA sequencing is required to identify specific isoforms
  • LOD: 5%
  • Assay includes Primers-Mastermix Mix and positive controls
  • Requires HRM-enabled RT-PCR (example Thermo Fisher™ Quantstudio 3 or higher)
Specifications

Specifications

3 x 5 mL Tube Primer Sets, 4 x 1.5 mL Tube Mutant Controls. Store at -20°C
PCR Instruments
20 Samples
Dry Ice
HRM
Yes
0.95
>99%
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