Precipio™ HemeScreen CLL Panel-3

Catalog No. 22-021-972

Supplier: Precipio™ HS3PCLL

Description

The HemeScreen CLL Panel-3 is an RUO pre-plated kit used to detect CLL-related gene mutations for MYD88, NOTCH1, CXCR4, and SF3B1 genes through HRM methods.

HemeScreen is a proprietary set of RUO (Research Use Only) reagents used to screen the wild type (Negative) from Mutated (Positive) genes in a simplified workflow relative to alternative molecular testing technologies (RT-PCR or NGS).

• Pre-plated configuration with embedded mutant, wild type, and NTC controls to run 3 samples in duplicate
• Simplified workflow and reduced chance of error
• Data capture during thermocycling
• Fast turnaround time
• Broad mutation detection (SNPs, Modifications, Indels)
• Low limits of detection
• Results are qualitative and DNA sequencing is required to identify specific isoforms
• LOD: 5%
• Assay includes Primers-Mastermix Mix and positive controls
• Requires HRM-enabled RT-PCR (example Thermo Fisher™ Quantstudio 3 or higher)

Specifications

• Content And Storage: 96-well Plate with Gene Targets, Positive, Negative, and Wild Type Controls. Store at -20°C
• Detection Method: HRM
• For Use With (Equipment): PCR Instruments
• Includes Label or Dye: Yes
• Quantity: 3 Samples
• Sensitivity: 0.95
• Shipping Condition: Dry Ice
• Target: MYD88, NOTCH1, CXCR4, SF3B1
• Target Specificity: >99%