Precipio™ HemeScreen Cytopenia Panel-3

Catalog No.	Quantity
22-021-971	3 Samples

Catalog No. 22-021-971 Supplier Precipio™ Supplier No. HS3PCTP

Description

The HemeScreen Cytopenia Panel-3 is an RUO pre-plated kit used to detect Cytopenia-related gene mutations for ASXL1, DNMT3A, RUNX1, WT1, and SF3B1 genes through HRM methods.

HemeScreen is a proprietary set of RUO (Research Use Only) reagents used to screen the wild type (Negative) from Mutated (Positive) genes in a simplified workflow relative to alternative molecular testing technologies (RT-PCR or NGS).

• Pre-plated configuration with embedded mutant, wild type, and NTC controls to run 3 samples in duplicate
• Simplified workflow and reduced chance of error
• Data capture during thermocycling
• Fast turnaround time
• Broad mutation detection (SNPs, Modifications, Indels)
• Low limits of detection
• Results are qualitative and DNA sequencing is required to identify specific isoforms
• LOD: 5%
• Assay includes Primers-Mastermix Mix and positive controls
• Requires HRM-enabled RT-PCR (example Thermo Fisher™ Quantstudio 3 or higher)

Specifications

• Content And Storage: 96-well Plate with Gene Targets, Positive, Negative, and Wild Type Controls. Store at -20°C
• Control Template: Non-template (NTC) Controls
• Detection Method: HRM
• Form: Liquid
• Format: Kit
• PCR Method: qPCR
• Technique: HRM
• Disease: Myeloproliferative Disorders
• For Use With (Equipment): PCR Instruments
• Gene Symbol: ASXL1, DNMT3A, RUNX1, SF3B1, WT1
• Includes Label or Dye: Yes
• Kit Type: HRM DNA Mutation Detection Kit
• Label or Dye: High Resolution Melting (HRM)
• No. of Tests: 3 Test
• Primer: PCR Primers
• Product Line: HemeScreen
• Product Type: Genotyping Kit
• Quantity: 3 Samples
• Sensitivity: 0.95
• Shipping Condition: Dry Ice
• Sufficient For: 3 Samples
• Target: ASXL1, DNMT3A, RUNX1, WT1, SF3B1
• Target Loci: ASXL1, DNMT3A, RUNX1, SF3B1, WT1
• Target Organism Class: Human
• Target Specificity: >99%
• For Use With (Application): Genotyping
• Compatibility: HRM-enabled RT-PCR Instruments
• No. of Reactions: 3 Reactions
• Reaction Format: Master Mix
• Sample Type: Whole Blood, Bone Marrow
• Starting Material: DNA
• Includes: 96-well plate with gene targets, positive controls, negative controls, wild type controls, primers and mastermix
• Storage Buffer: EDTA (60-90%), Glycerol (7-20%), Oligodeoxyribonucleic acid (0.01%), Sodium Azide (<0.1%)
• Color: Light Yellow to Colorless