Hemoglobin A (beta chain) Monoclonal Antibody (14G2.G11.F11), Rockland™

Mouse Monoclonal Antibody

Supplier:  Rockland Immunochemicals 200301GS4S

Catalog No. 50-199-0620

Description

Store vial at -20°C prior to opening. This product is stable at 4°C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use. Reacts specifically with human HbA beta chain isoform. This antibody does not react with the HbS form, HbF (gamma) form, HbC forms. HbA antibody cross reacts with HbA-2.

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon-gamma-G-gamma-A-delta-beta-3'.

Specifications

• Antigen: Hemoglobin A (beta chain)
• Classification: Monoclonal
• Concentration: 1.04 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: P68871
• Gene Symbols: HBB
• Immunogen: Anti-Hemoglobin A (beta chain) Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb beta-subunit conjugated to KLH.
• Regulatory Status: RUO
• Gene ID (Entrez): 3043
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot
• Clone: 14G2.G11.F11
• Conjugate: Unconjugated
• Gene: HBB
• Gene Alias: beta globin chain; Beta-1-globin; Beta-globin; CD113t-C; HBB; Hemoglobin beta chain; hemoglobin beta chain complex; Hemoglobin beta chain, major-form; Hemoglobin beta-1 chain; Hemoglobin subunit beta; Hemoglobin subunit beta-1; hemoglobin, beta; III beta-1 globin; III beta-2 globin; LVV-hemorphin-7; Spinorphin
• Host Species: Mouse
• Quantity: 25 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a λ