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Invitrogen™ Hemoglobin alpha Recombinant Rabbit Monoclonal Antibody (PD00-16)
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Catalog No. FEMA550713
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FEMA550713 100 μL
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Catalog No. FEMA550713 Supplier Invitrogen™ Supplier No. MA550713
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Description

Rabbit Recombinant Monoclonal Antibody

Positive control: Rat heart tissue lysates, human bone marrow tissue, human liver tissue, human placenta tissue, mouse brain tissue, human spleen tissue. Predicted band size: 15 kDa Subcellular Location: Cytosol, cytosolic small ribosomal subunit, hemoglobin complex, blood microparticle, extracellular exosome, extracellular region, extracellular space, endocytic vesicle lumen, haptoglobin-hemoglobin complex, membrane.

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Hemoglobin alpha
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone PD00-16
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Hba1
Gene Accession No. P01942, P01946, P69905
Gene Alias alpha 1 globin; alpha globin 1; alpha one globin; alpha-1/2-globin; alpha-2 globin chain; alpha-globin; delta globin; GloA; globin, alpha; haemaglobin alpha 1; Hba; HBA1; HBA2; Hba-a1; Hba-a2; HBAM; Hbat1; HBA-T3; HBH; hemoglobin alpha 1 chain; hemoglobin alpha 1 globin chain; hemoglobin alpha chain; hemoglobin alpha, adult chain 1; hemoglobin alpha, adult chain 2; hemoglobin alpha-1/2 chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin subunit alpha-1/2; hemoglobin, alpha 1; LOC287167
Gene Symbols Hba, Hba-a1, Hba1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to Human Hemoglobin alpha aa 50-150.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15121, 15122, 25632, 287167, 3039
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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