Hemoglobin beta A-2 Monoclonal Antibody (21G1.F1.B9.G9.D11), Rockland™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-0627	Rockland Immunochemicals 200301GS8	100 μg
50-199-0628	Rockland Immunochemicals 200301GS8S	25 μL

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Reacts specifically with human HbA-2 delta isoform. This antibody does not react with the HbA, HbS, HbC, or HbF isoforms.

Hemoglobin subunit delta is a protein that in humans is encoded by the HBD gene. The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon-Ggamma-Agamma-delta-beta-3'.

Specifications

• Antigen: Hemoglobin beta A-2
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Alias: delta globin; Delta-globin; delta-globin chain; HBD; Hemoglobin delta chain; Hemoglobin subunit delta; hemoglobin, delta
• Gene Symbols: HBD
• Isotype: IgG1 κ
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: HBD

• Clone: 21G1.F1.B9.G9.D11
• Applications: ELISA, Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P02042
• Gene ID (Entrez): 100187828, 3045
• Immunogen: Anti-Hemoglobin beta A-2 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb delta-subunit conjugated to KLH.
• Primary or Secondary: Primary
• Product Type: Antibody