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Invitrogen™ Hemoglobin Monoclonal Antibody (9A5)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MIH9506
Description
MIH9506 targets Hemoglobin in ELISA, IP, and RIA applications and shows reactivity with Human samples. The MIH9506 immunogen is human Hemoglobin. MIH9506 detects Hemoglobin which has a predicted molecular weight of approximately 15 kDa. MIH9506 was formerly sold as a Seradyn product.
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Specifications
Hemoglobin | |
Monoclonal | |
5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.4 | |
P68871, P69905 | |
HBA1, HBB | |
Human Hemoglobin. | |
1 mg | |
Primary | |
Human | |
Antibody | |
IgG |
ELISA, Immunoprecipitation, Radioimmune Assays (RIA) | |
9A5 | |
Unconjugated | |
HBA1 | |
alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin chain; Alpha-globin; ALPHA-GLOBIN GENE; delta globin; Haemoglobin; Hb; HBA1; HbA1c; HBA2; HBA-T3; HBH; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin, alpha 1 | |
Mouse | |
Ion-exchange chromatography | |
RUO | |
3039, 3043 | |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C | |
Liquid |
Safety and Handling
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