Invitrogen™ Hemoglobin Monoclonal Antibody (9A5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA514719

Catalog No. PIMA514719

Description

MA5-14719 targets Hemoglobin in ELISA, IP, and RIA applications and shows reactivity with Human samples. The MA5-14719 immunogen is human Hemoglobin. MA5-14719 detects Hemoglobin which has a predicted molecular weight of approximately 15 kDa. Product MA514719 is a smaller package size of MIH9506 (formerly sold as a Seradyn product).

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Specifications

• Antigen: Hemoglobin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P68871, P69905
• Gene Symbols: HBA1, HBB
• Immunogen: Human Hemoglobin.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunoprecipitation, Radioimmune Assays (RIA)
• Clone: 9A5
• Conjugate: Unconjugated
• Gene: HBA1
• Gene Alias: alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin chain; Alpha-globin; ALPHA-GLOBIN GENE; delta globin; Haemoglobin; Hb; HBA1; HbA1c; HBA2; HBA-T3; HBH; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin, alpha 1
• Host Species: Mouse
• Purification Method: Ion-exchange Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3039, 3043
• Content And Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Form: Liquid