Heparan Sulfate Proteoglycan 2 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-6315	100 μL

Catalog No. 50-198-6315 Supplier Bioss Supplier No. BS5072R

Description

Rabbit Polyclonal Antibody

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion.

Specifications

• Antigen: Heparan Sulfate Proteoglycan 2
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: MRGPRX2
• Gene Accession No.: Q96LB1
• Gene Alias: G protein-coupled receptor MRGX2; MAS related GPR family member X2; Mas-related G protein-coupled receptor G3; MAS-related GPR, member X2; Mas-related G-protein coupled receptor member X2; MGRG3; MRGPRX2; MRGX2
• Gene Symbols: MRGPRX2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Heparan Sulfate Proteoglycan 2.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 117194
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG