Invitrogen™ Heparin Cofactor II Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110356

Catalog No. PIPA5110356

Description

Immunogen sequence: GSKGPLDQLE KGGETAQSAD PQWEQLNNKN LSMPLLPADF HKENTVTNDW IPEGEEDDDY LDLEKIFSED DDYIDIVDSL SVSPTDSDVS AGNILQLFHG KSRIQRLNIL NAKFAFNLYR VLKDQVNTFD NIFIAPVGIS TAMGMISLGL KGETHEQVHS ILHFKDFVNA SSKYEITTIH NLFRKLTHRL FRRNFGYTLR SVNDLYIQKQ FPILLDFKTK VREYYFAEAQ IADFSDPAFI SKTNNHIMKL TKGLIKDALE NIDPATQMMI L.

The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.

Specifications

• Antigen: Heparin Cofactor II
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Serpind1
• Gene Alias: AA985900; AI303446; D22S673; HC2; Hcf2; HCII; HC-II; Heparin cofactor 2; heparin cofactor II; HLS2; leuserpin 2; leuserpin-2; LS2; Protease inhibitor leuserpin-2; rls2var1; serine (or cysteine) peptidase inhibitor, clade D, member 1; serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; serine (or cysteine) proteinase inhibitor, clade D, member 1; serpin D1; serpin family D member 1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Serpind1; THPH10
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15160, 3053
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.22 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P05546, P49182
• Gene Symbols: Serpind1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-290 of human SERPIND1 (NP_000176.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov