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Invitrogen™ Hepatitis B Virus preS2 Polyclonal Antibody
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Catalog No. PA14105
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100 μg
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PA14105 100 μg
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Catalog No. PA14105 Supplier Invitrogen™ Supplier No. PA14105
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Description

Rabbit Polyclonal Antibody

PA1-4105 detects the Hepatitis B Virus. PA1-4105 has been successfully used in Western blot procedures. The PA1-4105 immunogen is a synthetic peptide corresponding to residues C(132) Q D P R V R G L Y F P A G G(145) of preS2 HBV.

The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. The HBV surface protein antigens (HBsAg) are comprised of three carboxyl co terminal HBs proteins termed large (LHBs), middle (MHBs) and small (SHBs, also called major) protein. LHBs and MHBs also share the highly hydrophobic, repetitive, membrane spanning S domain. In addition, MHBs has a 55 amino acid region called preS2. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Hepatitis B Virus preS2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Alias HBV; HBVgp4; hepatitis b virus pre-s receptor fragment; HepB; pre-s2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues C(132) Q D P R V R G L Y F P A G G(145) of preS2 HBV.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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