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Hepatitis B Virus Surface Monoclonal Antibody (T9), Invitrogen™

Catalog No. PIMA513059
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500 μL
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PIMA513059 500 μL
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Catalog No. PIMA513059 Supplier Thermo Scientific Supplier No. MA513059

Mouse Monoclonal Antibody

MA5-13059 targets Hepatitis B Virus Surface Antigen in IHC (P) applications and shows reactivity with Human samples. The MA5-13059 immunogen is purified HbsAg, subtype ayw3. Ab-1 recognizes a protein in the outer surface coat of hepatitis B virus.

The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. The HBV surface protein antigens (HBsAg) are comprised of three carboxyl co terminal HBs proteins termed large (LHBs), middle (MHBs) and small (SHBs, also called major) protein. LHBs and MHBs also share the highly hydrophobic, repetitive, membrane spanning S domain. In addition, MHBs has a 55 amino acid region called preS2. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Hepatitis B Virus Surface
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone T9
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation tissue culture supernatant with 0.09% sodium azide
Gene Alias HBsAg; HBV; hepatitis b virus surface antigen; HepB
Host Species Mouse
Immunogen Purified HbsAg, subtype ayw3
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1 λ
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