Invitrogen™ Hepatitis C Virus NS3 Monoclonal Antibody (F39C)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA17355

Catalog No. PIMA17355

Description

The MA1-7355 antibody reacts with Hepatitis C virus NS3 in viral and infected tissue samples. This antibody is reactive towards genotypes 1a, 1b, and 2a. MA1-7355 has been successfully used in ELISA, Immunofluorescence and Western blot applications. The MA1-7355 antibody was raised against HCV NS3 protein.

Hepatitis C virus (HCV) is a small (55-65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans. Nonstructural protein 3 (NS3), also known as p-70, is a viral nonstructural protein that is 70 kDa cleavage product of the hepatitis C virus polyprotein. It acts as a serine protease. C-terminal two thirds of the protein also acts as helicase and nucleoside triphosphatase. First (N-terminal) 180 aminoacids of NS3 has additional role as cofactor domains for NS2 protein.

Specifications

• Antigen: Hepatitis C Virus NS3
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: F39C
• Conjugate: Unconjugated
• Gene Alias: HCV; HCV NS3; Hepatitis C Virus; HepC; HepC NS3
• Immunogen: NS3 protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov