Invitrogen™ Hepatitis E Virus Monoclonal Antibody (S-13)

Catalog No.	Quantity
PIMA121400	250 μg

Catalog No. PIMA121400 Supplier Invitrogen™ Supplier No. MA121400

Description

Mouse Monoclonal Antibody

This antibody does not cross-react with HCV-S, HCV-NS3, or HCV-NS4 protein.

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis, mainly transmitted via the fecal-oral route, often through contaminated water. HEV is a positive-sense single-stranded RNA virus belonging to the Hepeviridae family. Human HEV infections are primarily caused by genotypes 1 and 2, which are restricted to humans, while genotypes 3 and 4 are zoonotic and also infect various animals such as pigs and deer. HEV is known for its broad host range and potential to cause epidemics, leading to significant morbidity and mortality, especially in pregnant women. Recent studies have highlighted the extrahepatic manifestations of HEV, including neurological, renal, and hematological complications. HEV infections often result in self-limited acute hepatitis; however, chronic HEV infections can occur in immunocompromised individuals.

Specifications

• Antigen: Hepatitis E Virus
• Applications: ELISA
• Classification: Monoclonal
• Clone: S-13
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.2
• Gene Alias: HepE; HEV
• Host Species: Mouse
• Immunogen: Synthetic peptide (Human) consisting of essential sequences at least 30 residues in length which were selected from gene encoding ORF3 region of a Chinese HEV strain.
• Purification Method: Antigen affinity chromatography
• Quantity: 250 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgM