Invitrogen™ Hepatitis E Virus Polyclonal Antibody

Catalog No.	Quantity
PA14101	100 μg

Catalog No. PA14101 Supplier Invitrogen™ Supplier No. PA14101

Description

Rabbit Polyclonal Antibody

PA1-4101 detects the hepatitis E virus (HEV) variant identified in the United States, designated HEV US-u3-2e. PA1-4101 has been successfully used in Western blot procedures. The PA1-4101 immunogen is a synthetic peptide corresponding to residues C(627) P E C R T L G L Q G(637) of the HEV capsid protein.

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis, mainly transmitted via the fecal-oral route, often through contaminated water. HEV is a positive-sense single-stranded RNA virus belonging to the Hepeviridae family. Human HEV infections are primarily caused by genotypes 1 and 2, which are restricted to humans, while genotypes 3 and 4 are zoonotic and also infect various animals such as pigs and deer. HEV is known for its broad host range and potential to cause epidemics, leading to significant morbidity and mortality, especially in pregnant women. Recent studies have highlighted the extrahepatic manifestations of HEV, including neurological, renal, and hematological complications. HEV infections often result in self-limited acute hepatitis; however, chronic HEV infections can occur in immunocompromised individuals.

Specifications

• Antigen: Hepatitis E Virus
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% sodium azide
• Gene Alias: HepE; HEV
• Host Species: Rabbit
• Immunogen: Synthetic peptide corresponding to residues C(627) P E C R T L G L Q G(637) of the HEV capsid protein.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG