Invitrogen™ HERC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5140038

Catalog No. PIPA5140038

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: AQVPMEYNHL QEIPIIALRN RLLLLHHLSE LFCPCIPMFD LEGSLDETGL GPSVGFDTLR GILISQGKEA AFRKVVQATM VRDRQHGPVV ELNRIQVKRS RSK Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 99%.

Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions.

Specifications

• Antigen: HERC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HERC2
• Gene Alias: D15F32S1h; D15F37S1; D7H15F32S1; D7H15F37S1; E3 ubiquitin-protein ligase HERC2; hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2; HECT and RLD domain containing E3 ubiquitin protein ligase 2; hect domain and RCC1-like domain-containing protein 2; hect domain and RLD 2; HECT-type E3 ubiquitin transferase HERC2; HERC2; Jdf2; Kiaa0393; mKIAA0393; MRT38; p528; probable E3 ubiquitin-protein ligase HERC2; rjs; SHEP1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8924
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95714
• Gene Symbols: HERC2
• Immunogen: Recombinant protein corresponding to Human HERC2. Recombinant protein control fragment (Product #RP-109391).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG