Invitrogen™ HERC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597119

Catalog No. PIPA597119

Description

Immunogen sequence: MLCWGYWSLG QPGISTNLQG IVAEPQVCGF ISDRSVKEVA CGGNHSVFLL EDGEVYTCGL NTKGQLGHER EGNKPEQIGA LADQHIIHVA CGESHSLALS DRGQLFSWGA GSDGQLGLMT TEDSVAVPRL IQKLNQQTIL QVSCGNWHCL ALAADGQFFT WGKNSHGQLG LGKEFPSQAS PQRVRSLEGI PLAQVAAGGA; Positive Samples: SH-SY5Y, U-87MG, A-431, Mouse lung, Mouse spinal cord; Cellular Location: Cytoplasm, Cytoplasmic vesicle.

This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: HERC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HERC3
• Gene Alias: 5730409F18Rik; AI646603; HECT and RLD domain containing E3 ubiquitin protein ligase 3; HECT domain and RCC1-like domain-containing protein 3; hect domain and RLD 3; HECT-type E3 ubiquitin transferase HERC3; HERC3; KIAA0032; mKIAA0032; Probable E3 ubiquitin-protein ligase HERC3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 73998, 8916
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.09 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q15034
• Gene Symbols: HERC3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HERC3 (NP_0554211).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG