Invitrogen™ HERC6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542322

Catalog No. PIPA542322

Description

Peptide sequence: LSKDSQVFSW GKNSHGQLGL GKEFPSQASP QRVRSLEGIP LAQVAAGGAH Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%.

HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).

Specifications

• Antigen: HERC6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HERC6
• Gene Alias: 1700121D12Rik; 2510038N07Rik; 4930427L17Rik; AI451296; CEB1; E3 ISG15--protein ligase Herc6; FLJ20637; HECT and RLD domain containing E3 ubiquitin protein ligase family member 6; HECT domain and RCC1-like domain-containing protein 6; hect domain and RLD 5; hect domain and RLD 6; HECT-type E3 ubiquitin transferase HERC6; Herc5; HERC6; potential ubiquitin ligase; probable E3 ubiquitin-protein ligase HERC6
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55008
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8IVU3
• Gene Symbols: HERC6
• Immunogen: Synthetic peptide directed towards the N-terminal of human HERC6 (aa 143-192).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG