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Invitrogen™ HERV-FRD Polyclonal Antibody
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Catalog No. PIPA5109694
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100 μL
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PIPA5109694 100 μL
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Catalog No. PIPA5109694 Supplier Invitrogen™ Supplier No. PA5109694
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AYRHPDFPLL EKAQQLLQST GSPYSTNCWL CTSSSTETPG TAYPASPREW TSIEAELHIS YRWDPNLKGL MRPANSLLST VKQDFPDIRQ KPPIFGPIFT NINLMGIAPI CVMAKRKNGT NVGTLPSTVC NVTFTVDSNQ QTYQTYTHNQ FRHQPRFPKP PNITFPQGTL LDKSSRFCQG RPSSCSTRNF WFRPADYNQC LQISNLSSTA EWVLLDQTRN SLFWENKTKG ANQSQ.

Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 145μ543]).[supplied by OMIM].
TRUSTED_SUSTAINABILITY

Specifications

Antigen HERV-FRD
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ERVFRD-1
Gene Accession No. P60508
Gene Alias Endogenous retrovirus group FRD member 1; endogenous retrovirus group FRD, member 1; envelope glycoprotein syncytin-A; envelope polyprotein; envFRD; ERVFRD-1; ERVFRDE1; FLJ41944; FLJ90611; GLLL6191; Gm52; HERV-FRD; HERV-FRD provirus ancestral Env polyprotein; HERV-FRD_6p24.1 provirus ancestral Env polyprotein; HERV-W/FRD; MGC87585; SU; Surface protein; Syna; Synb; syncytin 2; syncytin a; Syncytin2; syncytin-2; TM; Transmembrane protein; UNQ6191; UNQ6191/PRO20218
Gene Symbols ERVFRD-1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 16-250 of human ERVFRD-1 (NP_997465.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 405754
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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