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Invitrogen™ HERV Polyclonal Antibody
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Catalog No. PIPA579220
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100 μg
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PIPA579220 100 μg
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Catalog No. PIPA579220 Supplier Invitrogen™ Supplier No. PA579220
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human K562 whole cell, human SH-SY5Y whole cell, human MCF-7 whole cell.

HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HERV
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene ERVW-1
Gene Accession No. Q9UQF0
Gene Alias endogenous retroviral family W, env(C7), member 1; endogenous retrovirus group W member 1; endogenous retrovirus group W, member 1; ENV; envelope glycoprotein; envelope polyprotein gPr73; envelope protein; Enverin; ENVW; Env-W; ERVW-1; ERVWE1; gp24; gp50; HERV7Q; HERV-7q; HERV-7q envelope protein; HERV-tryptophan envelope protein; HERVW; HERV-W Env glycoprotein; HERV-W envelope protein; HERV-W_7q21.2 provirus ancestral Env polyprotein; HERVWENV; HERV-W-ENV; human endogenous retrovirus W envC7-1 envelope protein; SU; Surface protein; Syncytin; syncytin A; syncytin-1; TM; Transmembrane protein
Gene Symbols ERVW-1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human ERVW-1 (406-435aa YYVNQSGIVTEKVKEIRDRIQRRAEELRNT).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 30816
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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