Invitrogen™ HERV Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA512286

Catalog No. PIPA512286

Description

HERV Polyclonal Antibody for Western Blot, IHC (P)

HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.

Specifications

• Antigen: HERV
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ERVW-1
• Gene Alias: endogenous retroviral family W, env(C7), member 1; endogenous retrovirus group W member 1; endogenous retrovirus group W, member 1; ENV; envelope glycoprotein; envelope polyprotein gPr73; envelope protein; Enverin; ENVW; Env-W; ERVW-1; ERVWE1; gp24; gp50; HERV7Q; HERV-7q; HERV-7q envelope protein; HERV-tryptophan envelope protein; HERVW; HERV-W Env glycoprotein; HERV-W envelope protein; HERV-W_7q21.2 provirus ancestral Env polyprotein; HERVWENV; HERV-W-ENV; human endogenous retrovirus W envC7-1 envelope protein; SU; Surface protein; Syncytin; syncytin A; syncytin-1; TM; Transmembrane protein
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 30816
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q9UQF0
• Gene Symbols: ERVW-1
• Immunogen: KLH conjugated synthetic peptide between 400-429 amino acids from the central region of human HERV (ERVWE1).
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG