Invitrogen™ HES2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA523479

Catalog No. PIPA523479

Description

HES2 Polyclonal Antibody for IHC (P)

Transcription factor HES-2, of the HES family of proteins, contains one basic helix-loop-helix (bHLH) domain and one orange domain. It is reported to express in vascular smooth muscle cells, and may have some role in their differentiation. Activation of Notch signaling pathway leads to activation of Hes family genes through the interaction between Notch intracellular domain and RBPSUH (CSL). Hes family proteins are mammalian homologs of Drosophila Hairy and Enhancer of split. The Hes family of transcriptional repressors are implicated in the cell fate determination of stem cells (or precursor cells) by suppressing the expression of tissue-specific transcriptional activators.

Specifications

• Antigen: HES2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HES2
• Gene Alias: bHLHb40; Class B basic helix-loop-helix protein 40; hairy and enhancer of split 2; hairy and enhancer of split 2 (Drosophila); hes family bHLH transcription factor 2; Hes2; Hes-2; Transcription factor HES-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15206, 29567, 54626
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA and 0.05% sodium azide
• Gene Accession No.: O54792, P35429, Q9Y543
• Gene Symbols: HES2
• Immunogen: Synthetic peptide (8 GDAAELRKSLKPLLEKRR 25) of HES-2 protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG