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Invitrogen™ HES2 Polyclonal Antibody
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Catalog No. PIPA5103137
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100 μL
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PIPA5103137 100 μL
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Catalog No. PIPA5103137 Supplier Invitrogen™ Supplier No. PA5103137
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total HES2.

Transcription factor HES-2, of the HES family of proteins, contains one basic helix-loop-helix (bHLH) domain and one orange domain. It is reported to express in vascular smooth muscle cells, and may have some role in their differentiation. Activation of Notch signaling pathway leads to activation of Hes family genes through the interaction between Notch intracellular domain and RBPSUH (CSL). Hes family proteins are mammalian homologs of Drosophila Hairy and Enhancer of split. The Hes family of transcriptional repressors are implicated in the cell fate determination of stem cells (or precursor cells) by suppressing the expression of tissue-specific transcriptional activators.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HES2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HES2
Gene Accession No. O54792, P35429, Q9Y543
Gene Alias bHLHb40; Class B basic helix-loop-helix protein 40; hairy and enhancer of split 2; hairy and enhancer of split 2 (Drosophila); hes family bHLH transcription factor 2; Hes2; Hes-2; Transcription factor HES-2
Gene Symbols HES2
Host Species Rabbit
Immunogen A synthesized peptide derived from human HES2(Accession Q9Y543), corresponding to amino acid residues R24-S74.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15206, 29567, 54626
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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