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HES2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982193
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50-198-2193 100 μL
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Catalog No. 50-198-2193 Supplier Bioss Supplier No. BS12383R
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Description

Rabbit Polyclonal Antibody

Transcription factor HES-2, of the HES family of proteins, contains one basic helix-loop-helix (bHLH) domain and one orange domain. It is reported to express in vascular smooth muscle cells, and may have some role in their differentiation. Activation of Notch signaling pathway leads to activation of Hes family genes through the interaction between Notch intracellular domain and RBPSUH (CSL). Hes family proteins are mammalian homologs of Drosophila Hairy and Enhancer of split. The Hes family of transcriptional repressors are implicated in the cell fate determination of stem cells (or precursor cells) by suppressing the expression of tissue-specific transcriptional activators.

Specifications

Antigen HES2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene HES2
Gene Accession No. Q9Y543
Gene Alias BHLHB40; Class B basic helix-loop-helix protein 40; Hairy and enhancer of split 2; hairy and enhancer of split 2 (Drosophila); hes family bHLH transcription factor 2; HES2; Hes-2; Transcription factor HES-2
Gene Symbols HES2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human HES2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54626
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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