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HES5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550676

Catalog No. PA550676


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Description

Description

The antibody detects endogenous levels of total HES5 protein.

Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 is reported to be a down stream effector of the Notch Signaling Pathway and is expressed in advanced ovarian serous adenocarcinomas as well as in cervical squamous carcinoma. Reports also suggest that HES5 is abundantly expressed in osteoarthritis along with Notch1 and Jagged1.
Specifications

Specifications

HES5
Polyclonal
Unconjugated
HES5
Liquid
HES5
Synthetic peptide corresponding to a region derived from internal residues of human hes family bHLH transcription factor 5
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1.8 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q5TA89, P70120, Q03062
BHLHB38
Rabbit
IgG
100 μL
-20°C
Primary
15208, 388585, 79225
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