Invitrogen™ HES5 Recombinant Rabbit Monoclonal Antibody (4S4U7)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538214

Catalog No. PIMA538214

Description

Positive Samples: Mouse brain, Mouse spleen, Rat brain, Rat spleen Immunogen sequence: SPKEKNRLRK PVVEKMRRDR INSSIEQLKL LLEQEFARHQ PNSKLEKADI LEMAVSYLKH SKAFVAAAGP KSLHQDYSEG YSWCLQEAVQ FLTLHAASDT QMKLLYHFQR PPAAPAAPAK EPKAPGAAPP P.

Hairy and Enhancer-of-split homologues 5 (HES5) isa helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 is reported to be a down stream effector of the Notch Signaling Pathway and is expressed in advanced ovarian serous adenocarcinomas as well as in cervical squamous carcinoma. Reports also suggest that HES5 is abundantly expressed in osteoarthritis along with Notch1 and Jagged1.

Specifications

• Antigen: HES5
• Classification: Recombinant Monoclonal
• Concentration: 0.9 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P70120, Q03062, Q5TA89
• Gene Symbols: HES5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 12-142 of human HES5 (Q5TA89).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 4S4U7
• Conjugate: Unconjugated
• Gene: HES5
• Gene Alias: BHLHB38; Class B basic helix-loop-helix protein 38; hairy and enhancer of split 5; hairy and enhancer of split 5 (Drosophila); hes family bHLH transcription factor 5; Hes5; Hes-5; RP3-395M20.5; Transcription factor HES-5
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15208, 388585, 79225
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov