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Invitrogen™ HES5 Recombinant Rabbit Monoclonal Antibody (4S4U7)
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Catalog No. PIMA538214
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PIMA538214 100 μL
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Catalog No. PIMA538214 Supplier Invitrogen™ Supplier No. MA538214
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: Mouse brain, Mouse spleen, Rat brain, Rat spleen Immunogen sequence: SPKEKNRLRK PVVEKMRRDR INSSIEQLKL LLEQEFARHQ PNSKLEKADI LEMAVSYLKH SKAFVAAAGP KSLHQDYSEG YSWCLQEAVQ FLTLHAASDT QMKLLYHFQR PPAAPAAPAK EPKAPGAAPP P.

Hairy and Enhancer-of-split homologues 5 (HES5) isa helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 is reported to be a down stream effector of the Notch Signaling Pathway and is expressed in advanced ovarian serous adenocarcinomas as well as in cervical squamous carcinoma. Reports also suggest that HES5 is abundantly expressed in osteoarthritis along with Notch1 and Jagged1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HES5
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 4S4U7
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene HES5
Gene Accession No. P70120, Q03062, Q5TA89
Gene Alias BHLHB38; Class B basic helix-loop-helix protein 38; hairy and enhancer of split 5; hairy and enhancer of split 5 (Drosophila); hes family bHLH transcription factor 5; Hes5; Hes-5; RP3-395M20.5; Transcription factor HES-5
Gene Symbols HES5
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15208, 388585, 79225
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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