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  5. Tocris Bioscience™ Hesperadin hydrochloride

Tocris Bioscience™ Hesperadin hydrochloride
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Catalog No. 398850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent Aurora kinase B inhibitor

ATP-competitive inhibitor of Aurora B kinase (IC50 = 250 nM). Prevents chromosome alignment and segregation; also induces polyploidy and prevents histone H3-Ser10 phosphorylation. Overrides the spindle assembly checkpoint and induces mitotic exit in monastrol - and taxol -treated HeLa cells.

Chemical Identifiers

CAS 422513-13-1
Molecular Formula C29H32N4O3S

Specifications

Quantity 50 mg
Formula Weight 553.12
Purity >99%
Molecular Weight (g/mol) 516.66
Chemical Name or Material Hesperadin hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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