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HEXO Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983799
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50-198-3799 100 μL
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Catalog No. 50-198-3799 Supplier Bioss Supplier No. BS15470R
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Description

Rabbit Polyclonal Antibody

RNA exonuclease that binds to the 3′-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2′ and 3′-hydroxyl groups at the last nucleotide of the histone 3′-end is required for efficient degradation of RNA substrates. Also able to degrade the 3′-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5′-ACCCA-3′ sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3′-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.

Specifications

Antigen HEXO
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ERI1
Gene Accession No. Q8IV48
Gene Alias 3 ′ exoribonuclease; 3′ exoribonuclease; 3110010F15Rik; 3′-5′ exonuclease ERI1; 3′-5′ exoribonuclease 1; 3′exo; 3′hexo; enhanced RNAi protein 1; enhanced RNAi three prime mRNA exonuclease homolog 1; Eri1; eri-1; Eri-1 homolog; exoribonuclease 1; HEXO; histone mRNA 3′ end-specific exonuclease; Histone mRNA 3′-end-specific exoribonuclease; Histone mRNA 3′-exonuclease 1; protei; Protein 3′hExo; RGD1308378; Thex1; three prime histone mRNA exonuclease 1; three prime mRNA exonuclease 1
Gene Symbols ERI1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human HEXO.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 90459
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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