Invitrogen™ HEY1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA568563

Catalog No. PIPA568563

Description

This target displays homology in the following species: Cow: 79%; Dog: 79%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 100%.

Hairy/enhancer-of-split related with YRPW motif protein 1 belongs to the HEY family and is a Notch Signaling Pathway Protein. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. It is a downstream effector of Notch signaling which may be required for cardiovascular development. It acts as transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. It represses transcription by the cardiac transcriptional activators GATA4 and GATA6. Hey1 is also reported to be expressed during development of the nervous system.

Specifications

• Antigen: HEY1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HEY1
• Gene Alias: AI316788; AI414254; basic helix-loop-helix protein OAF1; basic helix-loop-helix transcription factor; BC8; bHLH protein Hesr-1/Hey1; bHLHb31; cardiovascular basic helix-loop-helix factor 2; cardiovascular helix-loop-helix factor 2; CHF2; CHF-2; class B basic helix-loop-helix protein 31; Hairy and enhancer of split-related protein 1; Hairy/E(spl)-related with YRPW motif 1; hairy/enhancer-of-split related with YRPW motif 1; hairy/enhancer-of-split related with YRPW motif protein 1; hairy-related transcription factor 1; Herp1; Herp2; hes related family bHLH transcription factor with YRPW motif 1; Hesr1; HESR-1; hes-related family bHLH transcription factor with YRPW motif 1; HES-related repressor protein 1; HES-related repressor protein 2; HEY1; hey1 protein; hHRT1; HRT1; HRT-1; id:ibd1292; MGC1274; mHRT1; OAF1; zgc:110572
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 155437
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: 0
• Gene Symbols: HEY1
• Immunogen: synthetic peptide directed towards the middle region of human HEY1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov