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Invitrogen™ HGF Chimeric Recombinant Human Monoclonal Antibody (mh010)
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Catalog No. PIMA535993
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Quantity:
200 μg
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Catalog No. Quantity
PIMA535993 200 μg
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Catalog No. PIMA535993 Supplier Invitrogen™ Supplier No. MA535993
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Description

Human Recombinant Monoclonal Antibody

HGF Chimeric Recombinant Monoclonal Antibody for Neu

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HGF Chimeric
Applications Neutralization
Classification Recombinant Monoclonal
Clone mh010
Concentration 1.4 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Hgf
Gene Accession No. P14210
Gene Alias C230052L06Rik; DFNB39; Fibroblast derived tumor cytotoxic factor; fibroblast-derived tumor cytotoxic factor; F-TCF; hepatocyte growth factor; Hepatocyte growth factor (hepapoietin A; hepatocyte growth factor (hepapoietin A; scatter factor); Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain; Hepatopoeitin A; hepatopoeitin-A; HepatopoietinA; hepatopoietin-A; Hgf; HGF/SF; HGFB; HPTA; Lung fibroblast derived mitogen; lung fibroblast-derived mitogen; NK1; NK2; Scatter factor; scatter factor); SF; SF/HGF
Gene Symbols Hgf
Host Species Human
Immunogen Recombinant Human HGF/Hepatocyte Growth Factor protein.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3082
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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