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HGF Mouse anti-Human, Clone: 9B6, Bioss
SDP

Catalog No. 501979817
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50-197-9817 100 μL
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Catalog No. 50-197-9817 Supplier Bioss Supplier No. BSM51153M
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Description

Mouse Monoclonal Antibody

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.

Specifications

Antigen HGF
Applications Western Blot
Classification Monoclonal
Clone 9B6
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene Hgf
Gene Accession No. P14210
Gene Alias C230052L06Rik; DFNB39; fibroblast-derived tumor cytotoxic factor; F-TCF; Hepatocyte growth factor; hepatocyte growth factor (hepapoietin A; scatter factor); Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain; Hepatopoeitin A; hepatopoeitin-A; HepatopoietinA; Hepatopoietin-A; Hgf; HGF/SF; HGFB; HPTA; lung fibroblast-derived mitogen; NK1; NK2; Scatter factor; SF; SF/HGF
Gene Symbols Hgf
Host Species Mouse
Immunogen This HGF antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 521-554 amino acids from human HGF.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3082
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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