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Invitrogen™ HGK Monoclonal Antibody (3C7B5)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA515423
Description
MA5-15423 targets MAP4K4 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15423 immunogen is purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli.
MAP4K4 (HGK) is a serine/threonine kinase which plays an important role in stress-activated MAPK core signaling pathways, the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.
Specifications
HGK | |
Monoclonal | |
Conc. Not Determined | |
Ascites with 0.03% sodium azide | |
O95819 | |
MAP4K4 | |
Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli. | |
RUO | |
9448 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ELISA, Western Blot | |
3C7B5 | |
Unconjugated | |
MAP4K4 | |
9430080K19Rik; AU043147; AU045934; AW046177; epididymis secretory protein Li 31; FLH21957; FLJ10410; FLJ20373; FLJ90111; HEL-S-31; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; HGK; HPK/GCK-like kinase HGK; KIAA0687; Map4k4; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; mitogen activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; NCK interacting kinase; nck-interacting kinase; NIK; Ste20 group protein kinase HGK | |
Mouse | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
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