HHATL/GUP1 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS12315R

Catalog No. 50-198-2132

Description

The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S. cerevisiae Gup1. It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH. HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development.

Specifications

• Antigen: HHATL/GUP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HHATL
• Gene Alias: 1110011D13Rik; C3orf3; Glycerol uptake/transporter homolog; GUP1; GUP1 glycerol uptake/transporter homolog; Gup1, glycerol uptake/transporter homolog; hedgehog acyltransferase-like; Hedgehog acyltransferase-like protein; Hhatl; KIAA1173; MBOAT3; membrane bound O-acyltransferase domain containing 3; MSTP002; OACT3; Protein-cysteine N-palmitoyltransferase HHAT-like protein; RGD1311911
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 57467
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q9HCP6
• Gene Symbols: HHATL
• Immunogen: KLH conjugated synthetic peptide derived from human HHATL/GUP1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG