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Invitrogen™ HIF-2 alpha Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA585520
Description
Keep as concentrated solution. Predicted reactivity: Mouse (80%), Pig (83%). Positive Control: HepG2 (1% O2 treatment for 24hr). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.
Specifications
HIF-2 alpha | |
Polyclonal | |
Unconjugated | |
EPAS1 | |
basic-helix-loop-helix-PAS protein MOP2; bHLHe73; Class E basic helix-loop-helix protein 73; ECYT4; endothelial PAS domain protein 1; endothelial PAS domain protein 1b; endothelial PAS domain-containing protein 1; endothelial PAS domain-containing protein 1b; EPAS; Epas1; EPAS-1; epas1b; Hif like protein; HIF1 alpha-like factor; HIF-1-alpha-like factor; HIF-1alpha-like factor; HIF1alpha-like factor; HIF2 alpha; HIF-2 alpha; HIF2A; hif-2a; hif-2ab; HIF-2alpha; HIF-2-alpha; HIF2-alpha; HIF-related factor; HLF; HLF (HIF1alpha-like factor); HRF; hypoxia inducible factor 2 alpha; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia inducible transcription factor 2alpha; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha; Member of PAS protein 2; mHLF; MOP2; PAS domain-containing protein 2; PASD2; wu:fq36f01 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
2034 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunoprecipitation, Western Blot | |
1 mg/mL | |
PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
Q99814 | |
EPAS1 | |
Recombinant protein encompassing a sequence within the center region of human HIF2 alpha. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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