Invitrogen™ HIF-2 alpha Polyclonal Antibody, DyLight™ 650

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522694

Catalog No. PIPA522694

Description

Suggested positive control: hypoxic lysates.

HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.

Specifications

• Antigen: HIF-2 alpha
• Classification: Polyclonal
• Conjugate: DyLight 650
• Gene: EPAS1
• Gene Alias: basic-helix-loop-helix-PAS protein MOP2; bHLHe73; Class E basic helix-loop-helix protein 73; ECYT4; endothelial PAS domain protein 1; endothelial PAS domain protein 1b; endothelial PAS domain-containing protein 1; endothelial PAS domain-containing protein 1b; EPAS; Epas1; EPAS-1; epas1b; Hif like protein; HIF1 alpha-like factor; HIF-1-alpha-like factor; HIF-1alpha-like factor; HIF1alpha-like factor; HIF2 alpha; HIF-2 alpha; HIF2A; hif-2a; hif-2ab; HIF-2alpha; HIF-2-alpha; HIF2-alpha; HIF-related factor; HLF; HLF (HIF1alpha-like factor); HRF; hypoxia inducible factor 2 alpha; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia inducible transcription factor 2alpha; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha; Member of PAS protein 2; mHLF; MOP2; PAS domain-containing protein 2; PASD2; wu:fq36f01
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100348809, 100771160, 13819, 2034, 29452, 443286
• Content And Storage: 4°C, store in dark
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.64 mg/mL
• Formulation: 50mM sodium borate with 0.05% sodium azide
• Gene Accession No.: P97481, Q99814, Q9JHS1
• Gene Symbols: EPAS1
• Immunogen: A peptide derived from the C-terminus of mouse/human HIF-2 alpha protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit, Monkey, Sheep, Hamster, Fish, Reptile
• Product Type: Antibody
• Isotype: IgG