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Invitrogen™ HIF-2 alpha Recombinant Rabbit Monoclonal Antibody (JB24-42)
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Catalog No. PIMA534672
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PIMA534672 100 μL
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Catalog No. PIMA534672 Supplier Invitrogen™ Supplier No. MA534672
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: SiHa, rat lung tissue, human breast cancer tissue, human placenta tissue, mouse colon tissue, HUVEC.

HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.
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Specifications

Antigen HIF-2 alpha
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JB24-42
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene EPAS1
Gene Accession No. Q99814
Gene Alias basic-helix-loop-helix-PAS protein MOP2; bHLHe73; Class E basic helix-loop-helix protein 73; ECYT4; endothelial PAS domain protein 1; endothelial PAS domain protein 1b; endothelial PAS domain-containing protein 1; endothelial PAS domain-containing protein 1b; EPAS; Epas1; EPAS-1; epas1b; Hif like protein; HIF1 alpha-like factor; HIF-1-alpha-like factor; HIF-1alpha-like factor; HIF1alpha-like factor; HIF2 alpha; HIF-2 alpha; HIF2A; hif-2a; hif-2ab; HIF-2alpha; HIF-2-alpha; HIF2-alpha; HIF-related factor; HLF; HLF (HIF1alpha-like factor); HRF; hypoxia inducible factor 2 alpha; hypoxia inducible factor 2, alpha subunit; hypoxia inducible factor 2a; hypoxia inducible transcription factor 2alpha; hypoxia-inducible factor 2 alpha; hypoxia-inducible factor 2-alpha; Member of PAS protein 2; mHLF; MOP2; PAS domain-containing protein 2; PASD2; wu:fq36f01
Gene Symbols EPAS1
Host Species Rabbit
Immunogen Synthetic peptide within Human HIF-2 alpha aa 61-110.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2034
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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