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Invitrogen™ HIF3A Monoclonal Antibody (OTI2D2)
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Catalog No. PIMA526482
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Quantity:
100 μL
Catalog No. Quantity
PIMA526482 100 μL
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Catalog No. PIMA526482

Supplier: Invitrogen™ MA526482

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Description

Mouse Monoclonal Antibody

HIF3A Monoclonal Antibody for Western Blot, IHC (P)

Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1 alpha, HIF-1 beta (also designated Arnt 1), EPAS-1 (also designated HIF-2 alpha) and HIF-3 alpha, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1 alpha is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HIF3A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI2D2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene HIF3A
Gene Accession No. Q9Y2N7
Gene Alias Basic-helix-loop-helix-PAS protein MOP7; BHLHE17; Class E basic helix-loop-helix protein 17; HIF-3 alpha; HIF3 alpha 1; HIF3A; HIF-3A; HIF-3-alpha; HIF3-alpha; HIF3-alpha-1; hypoxia inducible factor 3 alpha; hypoxia inducible factor 3 alpha subunit; hypoxia inducible factor 3, alpha subunit; hypoxia inducible factor 3a; hypoxia inducible factor three alpha; hypoxia-inducible factor 3 alpha; hypoxia-inducible factor 3-alpha; Inhibitory PAS domain protein; IPAS; Member of PAS protein 7; Mop7; Neonatal and embryonic PAS protein; NEPAS; PAS domain-containing protein 7; PASD7
Gene Symbols HIF3A
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 355-669 of HIF3A produced in E.coli.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64344
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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