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HIF3A Monoclonal Antibody (OTI5B7), TrueMAB™, OriGene

Mouse Monoclonal Antibody
Supplier: OriGene TA800761

Description
Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1 alpha, HIF-1 beta (also designated Arnt 1), EPAS-1 (also designated HIF-2 alpha) and HIF-3 alpha, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1 alpha is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription.Specifications
HIF3A | |
Monoclonal | |
1 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
Q9Y2N7 | |
HIF3A | |
Human recombit protein fragment corresponding to amino acids 355-669 of human HIF3A produced in E.coli. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
Western Blot | |
OTI5B7 | |
Unconjugated | |
HIF3A | |
HIF-3A, HIF3-alpha-1, IPAS, MOP7, PASD7, bHLHe17 | |
Mouse | |
Affinity Chromatography | |
RUO | |
64344 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
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