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HIF3A Monoclonal Antibody (OTI5B7), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA800761

Encompass_Preferred

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Catalog No. 50-167-8536


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Description

Description

Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1 alpha, HIF-1 beta (also designated Arnt 1), EPAS-1 (also designated HIF-2 alpha) and HIF-3 alpha, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1 alpha is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription.
Specifications

Specifications

HIF3A
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9Y2N7
HIF3A
Human recombit protein fragment corresponding to amino acids 355-669 of human HIF3A produced in E.coli.
100 μL
Primary
Human
Antibody
IgG1
Western Blot
OTI5B7
Unconjugated
HIF3A
HIF-3A, HIF3-alpha-1, IPAS, MOP7, PASD7, bHLHe17
Mouse
Affinity Chromatography
RUO
64344
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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